API and Chiral Products

Active pharmaceutical intermediate molecules or API’s are the biologically active, highly potent ingredients in pharmaceutical drugs. These potent ingredients are usually present in enantiomeric form and in most cases one enantiomeric form may be harmful while the other form is the intended active ingredient for the drug. Therefore it is imperative that the intended active pharmaceutical intermediate is present in pure form in the drug. Orochem Technologies Inc. SMB chromatography purification process allows for a high purity and high recovery separation of the active pharmaceutical intermediate. For this reason, Orochem Technologies Inc. is at the forefront of API purification, we have purification process for several enantiomers (montelukast, s-valsartan, gemcitabine, and atorvastin) and pharmaceutical grade API (EPA, phosphotidyl choline, and phytonadione). We are dedicated to helping our customers worldwide in achieving this goal.

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Title Citation Cutomer Affiliation
Rotary valve apparatus for simulated moving bed separations Oroskar, Anil R. U.S. Patent 8,349,175, issued January 8, 2013. Orochem Technologies, Inc.
Process and adsorbent for separating ethanol and associated oxygenates from a biofermentation system Oroskar, Anil R., Deepak Sharma, David W. House, and Alice M. Havill. U.S. Patent 8,658,845, issued February 25, 2014. Orochem Technologies, Inc.
Purification of montelukast using simulated moving bed A.K. Mandal, K.J. Ranbhan, G.G. Pai, A. Agarwal, R.V. N. Rema, A. Oroskar Orochem Technologies, Inc.
Mannose production from palm kernel meal using simulated moving bed separation Anil R Oroskar, Naveen S Sudharsan, Priyanka Anil Oroskar, Omkar M Kulkarni US Patent 9163050 B2, 2012 Orochem Technologies, Inc.
SMB process for the purification of ethanol and butanediol with integrated regeneration Sharma, Deepak, Rahul K. Keswani, Wahab Mahmood, and Asha A. Oroskar. U.S. Patent 8,704,016, issued April 22, 2014. US Patent 8704016 B2, 2013 Orochem Technologies, Inc.
Recovery of highly pure alpha-tocotrienol from crude palm oil extract Oroskar, Anil, Deepak Sharma, Vanshidhar Singh, Anand Oroskar, and Gautham Oroskar. U.S. Patent 8,937,191, issued January 20, 2015. US Patent 8937191 B2, 2012 Orochem Technologies, Inc.