Oligonucleotides
SYNTHESIS AND ANALYSIS
Custom Oligo Synthesis Services
- DNA and RNA
- DNA-RNA hybrid
- HPLC quality
- CONFIRMATION OF OLIGO STRUCTURE BY MS
- PURITY BY HPLC AND IE
- Nano moles to micro moles scale
Options for Oligo Modifications
- Backbone modification
- Chimeric molecules – combination of DNA, RNA, LNA, 2’-OMe, and 2’Fluoro
- Amino, Thio and Biotin spacers
- Labeled probes (FAM, HEX, TET, ROX, Cy-3, Cy-5, etc.)
Our laboratory is equipped with synthesizers from nano moles to micro moles scale. Combined with strong analytical expertise enables us to complete any modification in oligo synthesis providing confirmation of the structure by MS and a certificate of purity for each molecule (HPLC-RP, IE).
High-throughput
Oligo Synthesis Plates
- Custom CPG dispensing
- 96-well and 384-well
PLEASE FILL UP THE REQUEST FORM FOR
OLIGO SYNTHESIS SERVICES BELOW
FILL THE FORM
Appendix: Letter Based Codes
| BaseID | 2-Letter | Verbose Code |
|---|---|---|
| A | dA | dA |
| C | dC | dC |
| G | dG | dG |
| T | dT | T |
| a | rA | rA |
| c | rC | rC |
| g | rG | rG |
| U | rU | U |
| t | 3T | idT |
| 1 | mA | r2’OMeA |
| 2 | mC | r2’OMeC |
| 3 | mG | r2’OMeG |
| 4 | mU | 2’OMeU |
| 5 | As | dA-s |
| 6 | Cs | dC-s |
| 7 | Gs | dG-s |
| 8 | Ts | T-s |
| 1s | r2’OMeA-s | |
| J | 2s | r2’OMeC-s |
| K | 3s | r2’OMeG-s |
| L | 4s | 2’OMeU-s |
| B | as | rA-s |
| E | cs | rC-s |
| F | gs | rG-s |
| H | us | U-s |
| n | 6n | AminoC6 |
| i | Tn | T-C6amino |
| b | bb | BiotinC6 |
| p | pp | Phos |
| u | rU | U |
| s | ss | C6-SS-C6- |
| m | n3 | C7-amino-3′ |
| h | al | 5′-Aldehyde 4FB |
| O | BT | Biotin-TEG |
| S | 18 | Spacer18 |
| f | FA | C6FAM |
| r | TA | TAMRA | P | HP | HydroxyProline |
| M | fA | r2’FluoroA |
| N | fC | r2’FluoroC |
| Q | fG | r2’FluoroG |
| R | fU | 2’FluoroU |
| I | dI | dInosine |
| o | Pn | C6Amino |
| q | Bp | BiotinPEG |
| V | n5 | 5’Amino5 |
| v | Bs | Biotin-Osu | W | TS | T(S2) |
| X | XX | XXX |
| Y | Cy | Cy3 |
| Z | sT | dT(thiol) |
| d | dB | Biotin |
| e | 3S | C3-Thiol |
| j | 8g | (8oxo_rg) |
| k | gg | glyceryl |
| l | NT | NHS-Carboxy-dT |
| w | dN | N |
| x | Ch | Cholesterol |
| y | 5B | Biotin-C4-amide-C4 | z | C5 | Cy5 |
| 9 | fI | 2fluoro_dI |
Orochem offers customized tools from
synthesis to purification
- From lab scale to prep scale
- Both Orochem brand or white label products
Orochem 96-Well Synthesis Plates
- 0.7 mL and 2 mL/well
- 7-, 10-, and 20- micron frits
- Available empty plate for customer choice of solid supports
- Available pre-packed with ZARA CPG
Orochem 96-Well Oroflex Filter Plates
- 0.7 mL and 2 mL/well
- 7-, 10-, and 20- micron frits
ZARA Oligo Deprotection Kit
- Rapid process for the cleavage, deprotection and recovery
- Perform at room temperature under organic condition
- Reduce the process time to 2 hours
- Easily automated
Phosphoramidites
for nucleic acid synthesis
DNA amidites, such as dA-N-Bz CEP,
dC-N-Ac CEP, dG-N-Ac CEP
and T-CEP
DNA amidites, such as dA-N-Bz CEP,
dC-N-Ac CEP, dG-N-Ac CEP
and T-CEP
Formats:
0.5, 1, 5, 10 g, and custom packing
HPLC and UHPLC columns
Orochem’s high quality Orosil Gold and
Reliasil C18, C8, 300A and 100A columns.
Reliasil C18, C8, 300A and 100A columns.
EZPRESS positive pressure processors
Formats:
96-well plate
48 cartridges
48 cartridges
Oligo Synthesis Services
- DNA, RNA, DHA-RNA hybrid
- Available desalted, OPC or HPLC-RP purification
QUIKVAP evaporators
Formats:
Single and double 96-well plate formats
Showing the single result
- Catalog#
- Description
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