Features

• Four different systems to meet different flow rate and output requirements
• Plug-and-Play systems including a pump module, control module with software, chromatography
  module, powered USB hub, 8-position adjustable column stand for holding various size columns,
• Other Accessories, like Water Bath, automatic Pump controller, and Inline detectors can be
  seamlessly attached to the system to get better productivity.
• Various empty columns sizes with different types of materials available to meet different separation
  requirement. All sizes, designed and manufactured by Orochem Technologies Inc.
• The columns are pre-packed with different stationary phase (either spherical or irregular)
  manufactured by Orochem Technologies Inc., to meet the process requirement.
• Optional method development services for conversion of single column data to continuous
  chromatography parameters on request
• Up to 90% cost reduction in resin and solvents/buffers

The Swan

The KingFisher

The Heron / The Concord

The Swan F10

The Swan F10 system is the smallest lab scale system offered by Orochem. The Swan F10 system is
designed to be used on a benchtop with a variety of small sized columns for lab scale applications.

The Swan F100

The Swan F100 system is designed for a small footprint to be used on a benchtop with a variety of medium sized columns for lab scale applications.

The Swan F300

The Swan F300 system is designed for a small footprint to be used on a benchtop with a variety of medium sized columns for lab scale applications.

Note: Products in The Swan series are sold exclusively for separation and purification of molecules having a molecular weight less than 5,000 Da, not including oligonucleotides and peptides

The KingFisher C Series System

The KingFisher C Series system is designed for a small footprint to be used on a benchtop with a variety of medium to large sized columns for pilot scale. Offered are two different variants of The KingFisher C series, one which has the same 8 column configuration as all of the other Chrome Prep systems, and one which has a 16 column configuration for larger projects.

The Heron C Series System

The Heron C series system is designed to be a pilot or commercial scale step up from The Swan F series. The Heron C series feature a rotary valve type and larger line sizes which can accommodate larger column sizes and higher throughput demands.

The Heron C080

The Heron C080 system is a larger system designed for pilot scale applications.

The Heron C016

The Heron C016 system is a larger system designed for pilot scale applications.

• Rotary valve
• 15 Column Configuration
• Flow rates up to 30 L/min
• Maximum Pressure 100 psi
• Floor mounted Pilot unit
• Approximate Throughput 100 kg per day
• Column Sizes 29 - 118 L
• Class 1/Div1 rated
• Sanitary Design

Figure 3: The Heron C016

The Concord T Series Systems

The Concord T series are custom designed SMB systems for commercial scale purifications. They are two different variants based on input capacity. The Concord T1000 is design for up to 1000 ton per annual, while The Concord T1500 is for up to 1500 ton per annual.

Symphony Chrome Pump

The Symphony Chrome Pump (Figure 4) is designed for use with the The Swan F and The KingFisher C Systems. The specifications for each type of pump are listed in Table 3. High-quality materials and rugged design make this pump a reliable performer over years of service.

Module	Minimum Flowrate (mL/min)	Maximum Flowrate (mL/min)	Flowrate Increments (mL/min)
The Swan F10	0	12	0.01
The Swan F100	0	100	0.1
The Swan F300	0	300	0.1

Table 2: Symphony Chrome Pump specificationsTable 2: Symphony Chrome Pump specifications

Figure 4: Symphony Chrome Pump

Features

• Dual self-flushing pump heads with overlapping cams for reduced pulsation
• Integrated pulse dampener Real-time pressure monitoring with upper/lower pressure limits
• Motor stall detector
• Prime/purge valve
• Prime button toggles flow rate to maximum for rapid solvent change
• Inlet and outlet ruby ball/sapphire seat check valves
• Tactile response, chemically resistant front panel keypad with LED display
• RS-232 serial and USB communication ports

Online UV-VIS Detector

The Symphony Chrome UV-VIS DCTR Detector (Figure 5) is engineered for seamless integration with Symphony Chrome SMB Systems.

Features

• Diode array design
• Dual light sources
• Flow rates up to 500 ml/mi
• LED display with touch pad for optional local control
• Simultaneous detection of up to 4 different wavelengths from 190 to 840 nm
• Preparative flow cells in PEEK and stainless steel from 0.3 to 2.4 mm path length
• Controlled by Symphony Chrome Screen software; capable of displaying output of two detectors in
  one window

Figure 5: The Symphony Chrome UV-VIS
DCTR Detector

Available Columns and Stationary Phases

Orochem provides a variety of different column sizes for all the Symphony Chrome SMB units. Columns can be sold filled with Orochem’s stationary phases, or empty so that they can be filled separately. Column sizes are listed in Table 3. Contact us for more options.
Orochem synthesizes and manufactures achiral and chiral stationary phases. For achiral phases, Orochem provides both silica based and polymer base, normal phases, reversed phases and ion- exchange phases. Orochem’s stationary phases are listed in Table 4. Contact us for more options.