Flash Chromatography Systems & Pre-Packed Columns
Flash Columns & Chromatography Systems
Orochem Technologies manufactures high-performance flash chromatography columns and partners with Santai Science to offer the SepaBean™ flash chromatography systems in the United States. Flash chromatography is a rapid, cost-effective form of preparative liquid chromatography that uses optimized pre-packed columns and high flow rates for faster separations. Our polypropylene and stainless steel column designs ensure safe handling, high pressure compatibility, and reproducible results.
What is Flash Chromatography?
Model | SepaBean™ machine U | SepaBean™ machine T | SepaBean™ machine | SepaBean™ machine 2 | SepaBean™ machine 2S | SepaBean™ machine L |
---|---|---|---|---|---|---|
Flow range (mL/min) | 1-100; 1-200 | 1-200 | 1-200 | 1-200 | 1-300 | 50-1000 |
Max. pressure (psi) | 100; 200 | 200 | 200 | 500 | 400 | 150 |
Gradients | 2 solvents, binary | 4 solvents binary with combination of any 2 | 4 solvents binary | 4 solvents binary with 3rdsolvents modifier | 4 solvents binary with 3rdsolvents modifier | 4 solvents binary with combination of any 2 |
Sample loading capacity | 10 mg – 33g | 10 mg – 33g | 10 mg – 33g | 10 mg – 33g | 10 mg – 33g | 8g- 300 g |
Column sizes | 4 -330 g, up to 3 kg with adapters | 4 -330 g, up to 3 kg with adapters | 4 -330 g, up to 3 kg with adapters | 4 -330 g, up to 3 kg with adapters | 4 -330 g, up to 3 kg with adapters | 800g- 3kg |
EZY FLASH Columns (Luer-Lock Connections)
Pre-packed, leak-free polypropylene cartridges compatible with most flash chromatography systems. Supports high flow rates and offers improved reproducibility.
Features:
- Pre-packed disposable poly-propylene cartridges
- Leak Free up to 150 psi
- Proprietary dry packing procedure
- Lure-Lock end connections
- Compatibility with most flash chromatography systems
- Improved chromatographic performance and reproducibility
- Liquid sample injection
- Support work at higher flow rates
- Biotage SNAP compatible
Specifications
- Particle size irregular 40-60 microns or spherical 50 microns
- Mesh size: 230-400
- Pore Size: 60 Å
- NP, RP, IX available
- ize range: 4 – 330 g
EZY FLASH CARTRIDGE DIMENSIONS |
Flash cartridge 4 g, MP 200 psi |
Flash cartridge 12 g, MP 200 psi |
Flash cartridge 25 g, MP 200 psi |
Flash cartridge 40 g, MP 200 psi |
Flash cartridge 60 g, MP 200 psi |
Flash cartridge 80 g, MP 200 psi |
Flash cartridge 100 g, MP 150 psi |
Flash cartridge 120 g, MP 200 psi |
Flash cartridge 220 g, MP 150 psi |
Flash cartridge 330 g, MP 150 psi |
PHASES</td style="background-color: #d1bedb;"> | TYPE</td style="background-color: #d1bedb;"> | PARTICLE SIZE [µm]</td style="background-color: #d1bedb;"> |
Silica</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> | |
N-Alumina</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> | |
A-Alumina</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> | |
B-Alumina</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> | |
C18</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> | |
NH2</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> | |
CN</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> | |
DIOL</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> | |
SCX</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> | |
SAX</td style="background-color: #d1bedb;"> | irregular</td style="background-color: #d1bedb;"> | 40-63</td style="background-color: #d1bedb;"> |
spherical</td style="background-color: #d1bedb;"> | 50</td style="background-color: #d1bedb;"> |
Avalon Flash Columns (ISCO Compatible)
Orochem’s Avalon flash columns are Isco compatible. There are both high pressure ( 180 psi/12 bar) and low pressure (45 psi /3bar) flash columns.
Features:
- Clean , pre-packed disposable poly-propylene cartridges
- Leak Free guaranteed
- Tight particle size distribution
- Low Fines
- Neutral pH
- Controlled water content
- Good resolution and no tailing
- Better separation
- Higher plate count
- Purification can be carried out at higher flow rates
Specifications
- Particle size 40-60 microns
- Mesh size: 230-400
- Pore Size: 60 Å
Avalexa Flash Columns (Biotage SNAP Compatible)
Optimized for drug discovery and natural product purification with high sample load capacity and reduced solvent usage.
Features:
- Gives the best purification performance
- Tighter bands and narrower peaks for improved fractionation
- Delivers better separation, higher fraction purity and increased sample loads
- More loading capacity
- Less cartridge and solvent usage
- Increased separation efficiency
- Higher fraction purity
- High performance packing technology
- Greater cartridge consistency
Alexa Flash Columns (Low Pressure, Biotage Compatible)
Orochem’s Alexa flash columns (Biotage Compatible)are rated for low pressure 45psi /3bar. Cartridges are packed with symmetrical sorbent compression to ensure improved separation and reproducibility.
Features:
- Gives best purification performances under low pressure.
- Tighter bands and narrower peaks for improved fractions.
- Delivers better separation, higher fraction purity and increased sample loads.
- Low Fines
- Neutral Ph
- High performance packing technology.
- Greater cartridge consistency.
Specifications:
Particle size 40-60 microns
Mesh size: 230-400
Pore Size: 60A
Aqua Flash Columns (Jones Flash Master Compatible)
Orochem Aqua flash chromatography is Jones Flash master compatible, which is a rapid form of preparative flash column chromatography based on optimized pre-packed columns through which are pumped with solvent at a high flow rate. They are simple and economical approach to preparative liquid chromatography.
Features:
- Better and faster Solution
- Capacity of the sample can be doubled.
- Samples can be run at higher flow rates.
- Lower cartridge pressure drop.
ISOSPEED Flash Chromatography System
Industrial-scale purification system for kilo-scale compound isolation, available in NP, RP, chiral, and custom bonded phases. The ISOSPEED flash purification system brings together the quality, performance and reproducibility to make it ideal for large scale purifications.
- Solvent delivery system with flow control
- Inline sample loading
- Online-UV detection
- Cartridge loading and unloading cart
- N2 environment and leak detection port
Features:
- Single prep scale flash chromatography system
- Custom sizes availability based on customer requirements
- Cheaper than any other competitor brands
- Available in normal phase (NP), reversed phase (RP), Chiral or any other bonded phase
- Uses easy to install pre-packed ISOSPEED flash columns
- Ideal for post-synthesis purification of compounds at kilo scale
- cGMP and CIP compliant
- Unique swivel design for easy loading and unloading
Flash Chromatography Phases & Specifications
We offer a complete range of phases for flash chromatography:
- Silica (irregular or spherical)
- N-Alumina, A-Alumina, B-Alumina
- C18, NH2, CN, Diol, SCX, SAX
Particle sizes: 40–63 µm (irregular) or 50 µm (spherical)
Pore sizes: 60 Å
Available in normal phase, reversed phase, ion exchange (IX), and specialty chemistries.
Order Flash Chromatography Columns & Systems
Shop our full line of flash chromatography columns and SepaBean™ systems online, or contact our technical team for system specifications, phase selection, and pricing details.
- Application Note
- Flyer / Documents
Flash Chromatography System
