Flash Chromatography System

Flash Chromatography is a rapid form of preparative column chromatography based on optimized pre-packed columns through which are pumped solvent at a high flow rate. It is a simple and economical approach to preparative LC. Orochem provides two types of flash columns. One type is using polypropylene. It is safer than glass columns, with no risk of breakage. Another type is the ISOSPEED flash column; the column is made of stainless steel, which is compatible with higher flow rate and pressure.

All Orochem’s flash columns are packed with symmetrical sorbent compression to ensure improved separation and reproducibility.


Orochem Technologies is partnering with Santai Science to offer SepaBean™ machine flash chromatography systems in the Midwest. Santai Science was established in 2004 and focused on developing and providing separation and purification systems.

SepaBean™ does more than basic function of separation and purification, the flash chromatography system provides innovative approaches to technology learning and knowledge sharing.

Model SepaBean™
machine U 		SepaBean™
machine T 		SepaBean™
machine 		SepaBean™
machine 2 		SepaBean™
machine 2S 		SepaBean™
machine L
Flow range (mL/min) 1-100; 1-200 1-200 1-200 1-200 1-300 50-1000
Max. pressure (psi) 100; 200 200 200 500 400 150
Gradients 2 solvents, binary 4 solvents binary with combination of any 2 4 solvents binary 4 solvents binary with 3rdsolvents modifier 4 solvents binary with 3rdsolvents modifier 4 solvents binary with combination of any 2
Sample loading capacity 10 mg – 33g 8g- 300 g
Column sizes 4 -330 g, up to 3 kg with adapters 800g- 3kg
More Details

EZY FLASH

Orochem’s EZY FLASH flash columns are a novel product conveniently equipped with Lure-Lock connections compatible with most flash chromatography systems.

Features:

  • Pre-packed disposable poly-propylene cartridges
  • Leak Free up to 150 psi
  • Proprietary dry packing procedure
  • Lure-Lock end connections
  • Compatibility with most flash chromatography systems
  • Improved chromatographic performance and reproducibility
  • Liquid sample injection
  • Support work at higher flow rates
  • Biotage SNAP compatible

Specifications

  • Particle size irregular 40-60 microns or spherical 50 microns
  • Mesh size: 230-400
  • Pore Size: 60 Ă…
  • NP, RP, IX available
  • ize range: 4 – 330 g
EZY FLASH CARTRIDGE DIMENSIONS
Flash cartridge 4 g, MP 200 psi
Flash cartridge 12 g, MP 200 psi
Flash cartridge 25 g, MP 200 psi
Flash cartridge 40 g, MP 200 psi
Flash cartridge 60 g, MP 200 psi
Flash cartridge 80 g, MP 200 psi
Flash cartridge 100 g, MP 150 psi
Flash cartridge 120 g, MP 200 psi
Flash cartridge 220 g, MP 150 psi
Flash cartridge 330 g, MP 150 psi
PHASES TYPE PARTICLE SIZE [µm]
Silica irregular 40-63
spherical 50
N-Alumina irregular 40-63
spherical 50
A-Alumina irregular 40-63
spherical 50
B-Alumina irregular 40-63
spherical 50
C18 irregular 40-63
spherical 50
NH2 irregular 40-63
spherical 50
CN irregular 40-63
spherical 50
DIOL irregular 40-63
spherical 50
SCX irregular 40-63
spherical 50
SAX irregular 40-63
spherical 50

Avalon flash

Orochem’s Avalon flash columns are Isco compatible. There are both high pressure ( 180 psi/12 bar) and low pressure (45 psi /3bar) columns.

Features:

  • Clean , pre-packed disposable poly-propylene cartridges
  • Leak Free guaranteed
  • Tight particle size distribution
  • Low Fines
  • Neutral pH
  • Controlled water content
  • Good resolution and no tailing
  • Better separation
  • Higher plate count
  • Purification can be carried out at higher flow rates

Specifications

  • Particle size 40-60 microns
  • Mesh size: 230-400
  • Pore Size: 60 Ă…

Avalexa flash

Avalexa flash columns are Biotage SNAP compatible. Applications are drug discovery, sample clean-up, natural product purification and many more.

Features:

  • Gives the best purification performance
  • Tighter bands and narrower peaks for improved fractionation
  • Delivers better separation, higher fraction purity and increased sample loads
  • More loading capacity
  • Less cartridge and solvent usage
  • Increased separation efficiency
  • Higher fraction purity
  • High performance packing technology
  • Greater cartridge consistency

Alexa flash

Orochem’s Alexa flash columns (Biotage Compatible)are rated for low pressure 45psi /3bar.Cartridges are packed with symmetrical sorbent compression to ensure improved separation and reproducibility.

Features:

  • Gives best purification performances under low pressure.
  • Tighter bands and narrower peaks for improved fractions.
  • Delivers better separation, higher fraction purity and increased sample loads.
  • Low Fines
  • Neutral Ph
  • High performance packing technology.
  • Greater cartridge consistency.

Specifications:

Particle size 40-60 microns
Mesh size: 230-400
Pore Size: 60A

Aqua flash

Orochem Aqua flash chromatography is Jones Flash master compatible, which is a rapid form of preparative column chromatography based on optimized pre-packed columns through which are pumped with solvent at a high flow rate. They are simple and economical approach to preparative liquid chromatography.

Features:

  • Better and faster Solution
  • Capacity of the sample can be doubled.
  • Samples can be run at higher flow rates.
  • Lower cartridge pressure drop.

ISOSPEED Flash System

Orochem Flash chromatography unit is a system is widely used in industries for compound purification following organic synthesis. The system accommodates single ISOSPEED cartridge and consists of:

Solvent delivery system with flow control
Inline sample loading
Online-UV detection
Cartridge loading and unloading cart
N2 environment and leak detection port
The ISOSPEED flash purification system brings together the quality, performance and reproducibility to make it ideal for large scale purifications.

Features:

  • Single column prep scale flash chromatography system
  • Custom sizes availability based on customer requirements
  • Cheaper than any other competitor brands
  • Available in normal phase (NP), reversed phase (RP), Chiral or any other
  • bonded phase
  • Uses easy to install pre-packed ISOSPEED flash columns
  • Ideal for post-synthesis purification of compounds at kilo scale
  • cGMP and CIP compliant
  • Unique swivel design for easy loading and unloading

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