Description
Orochem’s REVA detergent removal resin specifically binds and removes high concentrations of a wide variety of detergents used in protein research for the preparation of biological samples. The resin is designed for the efficient removal of a wide variety of commonly used ionic, nonionic, and zwitterionic detergents from proteins and peptide samples with high sample recovery in a centrifuge format for 25 to 1000 μl samples. Detergent removal is based on the presence of a small hydrophobic cavity in the resin into which appropriately sized non-polar moieties such as detergents can enter to form an inclusion complex. The easy-to-use spin format is fast (less than 15 min) and significantly improves results over the standard drip column and batch methodologies with >95% removal of detergents. The resin is available in bulk resin slurries, 96-well plate format for high-throughput applications as well as in spin column format.
