• Catalog#
  • Description
  • Chiral Chromatography

    Chiral Chromatography (215)

    Chiral Chromatography

    Orochem Technologies offers a family of polysaccharide-based chiral stationary phases (CSPs) for liquid chromatography under the Epitomize brand name. The CSPs are available in particle sizes from 1.7 microns up to 300 microns, and columns can be ordered in many different configurations for use in UHPLC, HPLC, prep/semi-preparative LC, and simulated moving bed (SMB) chromatography. The Epitomize family of chiral stationary phases is composed of two series. Epitomize CSP-1 is based on derivatized polysaccharides that are coated onto modified silica gel.
    Epitomize CSP-2 is based on derivatized polysaccharides that are covalently-bound to silica gel. The best CSP for a given separation depends on several factors. For the racemate, these factors include structure, polarity, and the type and number of functional groups present. Although all of the CSPs are based on polysaccharides, each typically shows a different chiral response for the same racemate. This response can also change dramatically with the selection of mobile phase. Together, these CSPs permit the separation of a very broad range of racemates. Both the CSP-1 and CSP-2 Series can be used in normal phase, polar phase, reverse phase, and SFC. Standard modifiers are TEA, DEA, ethanolamine, TFA, acetic acid, etc. and the use level is typically around 0.1%. Each column is tested before packaging and a chromatogram with test conditions and column performance data is included.

    Epitomize CSP-1 Series

    The Epitomize CSP-1 Series of chiral stationary phases is based on derivatized polysaccharides that are coated onto modified silica gel. Typical of coated CSPs, they should not be used with certain solvents such as ketones (e.g., acetone), halogenated solvents (e.g., dichloromethane and chloroform), ethyl acetate, THF, MTBE, aromatics, or other aggressive solvents such as DMF and DMA. Such solvents may diminish or destroy the effectiveness of the CSP-1 Series of chiral stationary phases. The CSP-1 Series is shown in Table 1. CSP-1ZCellulose tris-(3-chloro-4-methylphenylcarbamate)
    CSP Chiral Phase
    CSP-1A Amylose tris-(3,5-dimethylphenylcarbamate)
    CSP-1C Cellulose tris-(3,5-dimethylphenylcarbamate)
    CSP-1J Cellulose tris-(4-methylbenzoate)

    Epitomize CSP-2 Series

    The Epitomize CSP-2 Series of chiral stationary phases is based on derivatized polysaccharides that are covalently-bound to silica gel. The covalent linkage permits the use of all typical organic solvents including ketones (e.g., acetone), halogenated solvents (e.g., dichloromethane and chloroform), ethyl acetate, THF, MTBE, aromatics, and other aggressive solvents such as DMF and DMA. The CSP-2 series allows the separation of many racemates that cannot be separated on coated CSPs due to solvent or mobile phase limitations. Due to the different bonding techniques used for the Epitomize CSP-1 Series and the CSP-2 Series, the user should expect some selectivity differences for some racemates. The CSP-2 Series is shown in Table 2.
    CSP Chiral Phase
    CSP-2A Amylose tris-(3,5-dimethylphenylcarbamate)
    CSP-2C Cellulose tris-(3,5-dimethylphenylcarbamate)
    CSP-2Z Cellulose tris-(3-chloro-4-methylphenylcarbamate)
  • Chromatography Solvents

    Chromatography Solvents (1)

    Chromatography Solvents

    Only for Sale in India
  • Flash Chromatography

    Flash Chromatography (157)

    Flash Chromatography

    Overview

    Flash Chromatography is a rapid form of preparative column chromatography based on optimized pre-packed columns through which are pumped solvent at a high flow rate. It is a simple and economical approach to preparative LC. Orochem provides two types of flash columns. One type is using polypropylene. It is safer than glass columns, with no risk of breakage. Another type is ISOSPEED flash column; column is made of stainless steel, which compatible with higher flow rate and pressure. All Orochem’s flash columns are packed with symmetrical sorbent compression to ensure improved separation and reproducibility.

    Avalon flash

    Orochem’s Avalon flash columns are Isco compatible. There are both high pressure ( 180 psi/12 bar) and low pressure (45 psi /3bar) columns. Features:
    • Clean , pre-packed disposable poly-propylene cartridges
    • Leak Free guaranteed
    • Tight particle size distribution
    • Low Fines
    • Neutral pH
    • Controlled water content
    • Good resolution and no tailing
    • Better separation
    • Higher plate count
    • Purification can be carried out at higher flow rates
    Specifications
    • Particle size 40-60 microns
    • Mesh size: 230-400
    • Pore Size: 60 Å

    Avalexa flash

    Avalexa flash columns are Biotage SNAP compatible. Applications are drug discovery, sample clean-up, natural product purification and many more. Features:
    • Gives the best purification performance
    • Tighter bands and narrower peaks for improved fractionation
    • Delivers better separation, higher fraction purity and increased sample loads
    • More loading capacity
    • Less cartridge and solvent usage
    • Increased separation efficiency
    • Higher fraction purity
    • High performance packing technology
    • Greater cartridge consistency

    Alexa flash

    Orochem’s Alexa flash columns (Biotage Compatible)are rated for low pressure 45psi /3bar.Cartridges are packed with symmetrical sorbent compression to ensure improved separation and reproducibility. Features:
    • Gives best purification performances under low pressure.
    • Tighter bands and narrower peaks for improved fractions.
    • Delivers better separation, higher fraction purity and increased sample loads.
    • Low Fines
    • Neutral Ph
    • High performance packing technology.
    • Greater cartridge consistency.
    Specifications: Particle size 40-60 microns Mesh size: 230-400 Pore Size: 60A

    Aqua flash

    Orochem Aqua flash chromatography is Jones Flash master compatible, which is a rapid form of preparative column chromatography based on optimized pre-packed columns through which are pumped with solvent at a high flow rate. They are simple and economical approach to preparative liquid chromatography. Features:
    • Better and faster Solution
    • Capacity of the sample can be doubled.
    • Samples can be run at higher flow rates.
    • Lower cartridge pressure drop.

    ISOSPEED Flash System

    Orochem Flash chromatography unit is a system is widely used in industries for compound purification following organic synthesis. The system accommodates single ISOSPEED cartridge and consists of: Solvent delivery system with flow control Inline sample loading Online-UV detection Cartridge loading and unloading cart N2 environment and leak detection port The ISOSPEED flash purification system brings together the quality, performance and reproducibility to make it ideal for large scale purifications. Features:
    • Single column prep scale flash chromatography system
    • Custom sizes availability based on customer requirements
    • Cheaper than any other competitor brands
    • Available in normal phase (NP), reversed phase (RP), Chiral or any other
    • bonded phase
    • Uses easy to install pre-packed ISOSPEED flash columns
    • Ideal for post-synthesis purification of compounds at kilo scale
    • cGMP and CIP compliant
    • Unique swivel design for easy loading and unloading
    Contact us for more information.
  • HPLC Column

    HPLC Column (652)

    HPLC Column

    Orochem Technologies provides a wide range of traditional liquid chromatography columns for analytical, preparative, and simulated moving bed chromatography (SMB) applications. Our HPLC and semi/prep columns are used globally in clinical diagnostics laboratories, industries (like pharmaceutical, biotech, food, nutraceutical), environmental and forensic testing laboratories.
    HPLC

    Reliasil

    Reliasil HPLC columns are designed for high efficiency (high plate count) and general utility. The proprietary silica gel manufacturing process yields a Gaussian particle size distribution, narrow pore-size distribution, and strong resistance to high pH. Phases: Silica, C1, C4, C8, C18, C30, NH2, CN, Phenyl, SCX, SAX, Diol, Polyamine, PFP pH Range: 2-8.5,

    Orosil

    Orosil HPLC columns are designed for the separation of polar, semi-polar, and nonpolar compounds at low to medium pH Phases: C8, C18 pH Range: 1.5-9.0 Orosil Polar C18 Orosil Polar C18 columns are particularly advantageous for difficult separations involving polar and semi-polar compounds. Phases: C18 pH Range: 1.5-9.0

    Prestige

    Prestige is Orochem Technologies’ next-generation of highly base-deactivated stationary phases. Double end-capping and narrow particle size range contributes to superior basedeactivation and low backpressure. Phases: C8, C18 pH Range: 2-8.5

    Matrix

    Matrix C18 uses base-deactivated, ultra-high purity silica gel, densely bonded to produce an inert material ideally suited for the analysis of basic compounds. The resulting hydrophobic surface is also stable over a wide pH range (2-9) to allow for excellent method flexibility. Matix C18 AQ- Polar analysis in high Aqueous Mobile phases. Interspersed with hydrophilic end-capping group. Phases: C8, C18, C18AQ, NH2, Polychrome pH Range: 2-9.0

    Monitor

    Monitor is a top-quality phase, providing excellent stability and reproducibility, and minimal secondary interaction. Monitor is a perfect choice for reversed phase separations requiring thoroughly base-deactivated columns, and excels in challenging pharmaceutical and peptide separations. We developed Monitor expressly for the chromatography of difficult-to-separate samples. Phases: silica, C8, C18 pH Range: 2-8
  • HPLC Vials

    HPLC Vials (1)

    HPLC Vials

    Orochem Technologies offers vials for HPLC, GC and storage. The volume is from 0.1 mL to 4 mL. Both glass and plastic vials, with or without insert. There are several types of caps and septa. HPLC vials fit into most major brands of HPLC autosamplers
  • Prep Chromatography

    Prep Chromatography (65)

    Prep Chromatography

    Orochem Technologies provides a wide range of reverse phase, normal phase and chiral prep/semi-prep HPLC columns. The particle size ranges from 5-50 µm, pore size ranges from 80-300 Å, and various dimensions.

    Reliasil

    Reliasil HPLC columns are designed for high efficiency (high plate count) and general utility. The proprietary silica gel manufacturing process yields a Gaussian particle size distribution, narrow pore-size distribution, and strong resistance to high pH. Phases: Silica, C1, C4, C8, C18, C30, NH2, CN, Phenyl, SCX, SAX, Diol, Polyamine, PFP pH Range: 2-8.5,

    Monitor

    Monitor is a top-quality phase, providing excellent stability and reproducibility, and minimal secondary interaction. Monitor is a perfect choice for reversed phase separations requiring thoroughly base-deactivated columns, and excels in challenging pharmaceutical and peptide separations. We developed Monitor expressly for the chromatography of difficult-to-separate samples. Phases: silica, C8, C18 pH Range: 2-8

    Epitomize

    Epitomize is chiral stationary phase, based on cellulose tris(3,5-dimethyl phenyl carbamate) coated on different spherical silica. Phases: CSP-1A, CSP-1C, CSP-1K, CSP-1Z
  • Quick Disconnect Column

    Quick Disconnect Column (1)

    Quick Disconnect Column

    Orochem provides custom packed Quick Disconnect Column. The column features reusable column hardware and Orpheus sorbents. It can be used for desalting, online solid phase extraction, and chromatographic separation.
  • UHPLC Column

    UHPLC Column (6)

    UHPLC Column

    Orochem Technologies Gazelle UHPLC columns offer the chromatographer significantly increased throughput, low solvent consumption, inline process monitoring, and improved LC-MS results. Gazelle is designed by Orochem Technologies, especially to yield higher sensitivity and reproducibility in less run time. Orochem uses a proprietary silica type A manufacturing process that yields a narrow particle size and pore size distribution, which gives you consistent and reproducible results. The hydrophobic spherical surface is also stable over a wide pH range (2-8) to allow for excellent method flexibility. Applications are in clinical diagnostics labs, pharmaceutical discovery and PK/TK studies.
    Advantages:
    • Good Resolution
    • Faster Analysis
    • High Sensitivity
    • Low band spreading
    • Saves Solvent
    Features:
    • Surface Area: 327 m2/g
    • Pore Size: 13.5 nm
    • Pore Volume: 1.10 mL/g
    • pH Range: 2-8
    • Particle Size: 1.7µm
Chiral HPLC Column File size: 1 MB Download
CSP-1A-5 micron column-Stilbene Oxide, trans File size: 112KB Download
CSP-1A-5 micron Column-Trogers Base File size: 114KB Download
CSP-1A-5micron Column-Benzoin File size: 110KB Download
CSP-1A-UHPLC Column-Benzoin File size: 112KB Download
CSP-1A-UHPLC Column-Flavanone File size: 112KB Download
CSP-1A-UHPLC Column-Mianserin File size: 112KB Download
CSP-1A-UHPLC Column-Stilbene Oxide, trans File size: 112KB Download
CSP-1A-UHPLC Column-Trogers Base File size: 136KB Download
CSP-1C-5 micron Column-Benzoin File size: 108KB Download
CSP-1C-5 micron Column-Bi-2-Naphthol File size: 132KB Download
CSP-1C-5 micron Column-Butanediol Dibenzoate File size: 111KB Download
CSP-1C-5 micron Column-Mianserin-HCl File size: 108KB Download
CSP-1C-5 micron Column-Warfarin File size: 111KB Download
CSP-1C-5 micron-Phenoxy-2-propanol, 1-_ File size: 111KB Download
CSP-1C-UHPLC Column-Stilbene Oxide, trans File size: 110KB Download
CSP-1J-5 micron Column-Naphthyl)ethanol_1-(1) File size: 110KB Download
CSP-1J-5 micron column-Stilbene Oxide, trans File size: 110KB Download
CSP-1J-UHPLC Column-Benzoin File size: 112KB Download
CSP-1J-UHPLC Column-Naphthyl)ethanol_1-(1- File size: 114KB Download
CSP-1J-UHPLC column-Naphthyl)ethanol_1-(2- File size: 113KB Download
CSP-1J-UHPLC Column-Stilbene Oxide, trans File size: 113KB Download
CSP-1K-5 micron Column-Flavanone File size: 119KB Download
CSP-1K-5 micron Column-Mianserin File size: 119KB Download
CSP-1Z-5 micron Column-Naphthyl)ethanol_1-(1 File size: 111KB Download
CSP-1Z-5 micron column-Phenoxy-2-propanol File size: 112KB Download
CSP-1Z-5 micron Column-Stilbene Oxide, trans File size: 119KB Download
CSP-1Z-5 micron Column-Tetrahydro-1-naphthol File size: 111KB Download
CSP-2C-5 micron Column-Bi-2-Naphthol File size: 130KB Download
CSP-2C-5 micron Column-Stilbene Oxide, trans File size: 112KB Download
CSP-2C-5 micron Column-Warfarin (2) File size: 112KB Download
CSP-2C-5 micron Column-Warfarin File size: 112KB Download
SFC-1Z-3 micron- Column-Napropamid File size: 123KB Download
SFC-CSP-1A-3 micron Column-Chlorpheniramine File size: 121KB Download
SFC-CSP-1A-3 micron Column-Phenoxy-2-propanol, 1- File size: 118KB Download
SFC-CSP-1A-3 micron Column-Propranolol File size: 120KB Download
SFC-CSP-1A-3 micron Column-Uniconazole File size: 170KB Download
SFC-CSP-1Z-3 micron Column-Acenaphthenol, 1- File size: 120KB Download
SFC-CSP-1Z-3 micron Column-Proglumide File size: 124KB Download