Chiral Chromatography

Orochem Technologies offers a family of polysaccharide-based chiral stationary phases (CSPs) for liquid chromatography under the Epitomize brand name. The CSPs are available in particle sizes from 1.7 microns up to 300 microns, and columns can be ordered in many different configurations for use in UHPLC, HPLC, prep/semi-preparative LC, and simulated moving bed (SMB) chromatography. The Epitomize family of chiral stationary phases is composed of two series. Epitomize CSP-1 is based on derivatized polysaccharides that are coated onto modified silica gel.

Epitomize CSP-2 is based on derivatized polysaccharides that are covalently-bound to silica gel. The best CSP for a given separation depends on several factors. For the racemate, these factors include structure, polarity, and the type and number of functional groups present. Although all of the CSPs are based on polysaccharides, each typically shows a different chiral response for the same racemate. This response can also change dramatically with the selection of mobile phase. Together, these CSPs permit the separation of a very broad range of racemates. Both the CSP-1 and CSP-2 Series can be used in normal phase, polar phase, reverse phase, and SFC. Standard modifiers are TEA, DEA, ethanolamine, TFA, acetic acid, etc. and the use level is typically around 0.1%.

Each column is tested before packaging and a chromatogram with test conditions and column performance data is included.

Showing 1–12 of 215 results

  • Catalog#
  • Description
CSP-1A-5 micron column-Stilbene Oxide, transFile size: 112KBDownload
CSP-1A-5 micron Column-Trogers BaseFile size: 114KBDownload
CSP-1A-5micron Column-BenzoinFile size: 110KBDownload
CSP-1A-UHPLC Column-BenzoinFile size: 112KBDownload
CSP-1A-UHPLC Column-FlavanoneFile size: 112KBDownload
CSP-1A-UHPLC Column-MianserinFile size: 112KBDownload
CSP-1A-UHPLC Column-Stilbene Oxide, transFile size: 112KBDownload
CSP-1A-UHPLC Column-Trogers BaseFile size: 136KBDownload
CSP-1C-5 micron Column-BenzoinFile size: 108KBDownload
CSP-1C-5 micron Column-Bi-2-NaphtholFile size: 132KBDownload
CSP-1C-5 micron Column-Butanediol DibenzoateFile size: 111KBDownload
CSP-1C-5 micron Column-Mianserin-HClFile size: 108KBDownload
CSP-1C-5 micron Column-WarfarinFile size: 111KBDownload
CSP-1C-5 micron-Phenoxy-2-propanol, 1-_File size: 111KBDownload
CSP-1C-UHPLC Column-Stilbene Oxide, transFile size: 110KBDownload
CSP-1J-5 micron Column-Naphthyl)ethanol_1-(1)File size: 110KBDownload
CSP-1J-5 micron column-Stilbene Oxide, transFile size: 110KBDownload
CSP-1J-UHPLC Column-BenzoinFile size: 112KBDownload
CSP-1J-UHPLC Column-Naphthyl)ethanol_1-(1-File size: 114KBDownload
CSP-1J-UHPLC column-Naphthyl)ethanol_1-(2-File size: 113KBDownload
CSP-1J-UHPLC Column-Stilbene Oxide, transFile size: 113KBDownload
CSP-1K-5 micron Column-FlavanoneFile size: 119KBDownload
CSP-1K-5 micron Column-MianserinFile size: 119KBDownload
CSP-1Z-5 micron Column-Naphthyl)ethanol_1-(1File size: 111KBDownload
CSP-1Z-5 micron column-Phenoxy-2-propanolFile size: 112KBDownload
CSP-1Z-5 micron Column-Stilbene Oxide, transFile size: 119KBDownload
CSP-1Z-5 micron Column-Tetrahydro-1-naphtholFile size: 111KBDownload
CSP-2C-5 micron Column-Bi-2-NaphtholFile size: 130KBDownload
CSP-2C-5 micron Column-Stilbene Oxide, transFile size: 112KBDownload
CSP-2C-5 micron Column-Warfarin (2)File size: 112KBDownload
CSP-2C-5 micron Column-WarfarinFile size: 112KBDownload
SFC-1Z-3 micron- Column-NapropamidFile size: 123KBDownload
SFC-CSP-1A-3 micron Column-ChlorpheniramineFile size: 121KBDownload
SFC-CSP-1A-3 micron Column-Phenoxy-2-propanol, 1-File size: 118KBDownload
SFC-CSP-1A-3 micron Column-PropranololFile size: 120KBDownload
SFC-CSP-1A-3 micron Column-UniconazoleFile size: 170KBDownload
SFC-CSP-1Z-3 micron Column-Acenaphthenol, 1-File size: 120KBDownload
SFC-CSP-1Z-3 micron Column-ProglumideFile size: 124KBDownload